Preacher is the story of Jesse Custer (Dominic Cooper, Agent Carter), a conflicted preacher in a small Texas town who is inhabited by a mysterious entity that allows him to develop a highly unconventional power. Jesse, his ex-girlfriend, Tulip (Ruth Negga, Agents of S.H.I.E.L.D.), and an Irish vampire named Cassidy (Joseph Gilgun, This Is England) embark on a journey to, literally, find God.